BDBM13076 6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide::BMCL182567 Compound 6a::Dichlothiazide::Hydro-D::Hydrochlorothiazide::Hypothiazide::JFD00715::Oretic::cid_3639

SMILES NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl

InChI Key InChIKey=JZUFKLXOESDKRF-UHFFFAOYSA-N

Data  59 KI  6 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13076   

TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM13076(6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiad...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed